This website provides information about laboratory diagnostic services. The analyses presented are not a therapy and do not replace medical diagnosis and treatment. Medical decisions are made exclusively by your attending physician.

Gene expression analysis tumor diagnostics is revolutionizing modern oncology by precisely decoding genetic activity patterns in cancer tissue. Gene expression analysis cancer diagnostics, rna sequencing tumor diagnostics, transcriptome analysis tumor diagnostics, biomarker profiling tumor diagnostics and expression patterns tumor diagnostics enable a completely new dimension of tumor characterization at the molecular level.

rna sequencing cancer diagnost ics uses state-of-the-art next-generation sequencing technologies to analyze gene activity in detail. Transcriptome analysis cancer diagnostics identifies specific expression profiles that are characteristic of different tumor subtypes. With biomarker profiling cancer diagnostics, oncologists can now determine therapeutic target structures with unprecedented accuracy.

The expressionsmuster cancer diagnostics create the basis for personalized treatment strategies and enable a precise prognosis based on the individual tumor biology.

Ferroptosis

SCIENTIFIC FINDINGS ON A FIELD OF RESEARCH

A factual presentation of the state of research on ferroptosis

Ferroptosis research provides new insights into cellular mechanisms and their potential relevance. Scientific studies investigate correlations with vitamin C administration and observe different reaction patterns in various tumor models. Specific observations have been made particularly in resistant cell lines, while at the same time substance interactions have been identified that could be relevant in experimental settings.

RESEARCH ISSUES IN ONCOLOGY

A central research interest is the question of which cell biological mechanisms could lead to the development of new approaches. Ferroptosis is a scientifically documented mechanism whose properties are currently being investigated in studies.

The following presentation is intended solely to provide information on the current state of scientific research. It does not constitute a treatment recommendation and does not replace medical advice.

tumor diagnostics cancer

RNA sequencing tumor diagnostics – high-resolution gene activity analysis

RNA sequencing tumor diagnostics enables the comprehensive analysis of all active genes in tumor cells with single-cell resolution. Rna sequencing tumor diagnostics identifies characteristic transcription profiles that define specific tumor types and subtypes. With rna sequencing tumor diagnostics, researchers can now precisely track the dynamic changes in gene expression during tumor development and identify therapeutic targets.

Transcriptome analysis tumor diagnostics – decoding the complete RNA landscape

Transcriptome analysis tumor diagnost ics provides a complete picture of all RNA molecules in tumor cells for comprehensive molecular characterization. Transcriptome analysis tumor diagnostics combines different RNA types such as mRNA, microRNA and long non-coding RNA for holistic tumor profiling. These transcriptome analysis tumor diagnostics approaches enable the discovery of new biomarkers and the development of targeted therapy strategies based on the individual tumor RNA signature.

Biomarker profiling tumor diagnostics – identifying therapeutic target structures

Biomarker profiling tumor diagnostics uses expression data to identify prognostic and predictive biomarkers for personalized treatment approaches. Biomarker profiling cancer diagnostics integrates machine learning and artificial intelligence for pattern recognition in complex gene expression data. With biomarker profiling tumor diagnostics, clinicians can now predict treatment response and identify resistance mechanisms at an early stage.

Expression patterns in tumor diagnostics – tumor signatures for precision medicine

Expression pattern tumor diagnost ics analyses characteristic gene activity profiles for precise tumor classification and prognosis. Expression pattern tumor diagnostics enables the development of molecular tumor subtyping that goes beyond morphological classifications. These expression pattern tumour diagnostics procedures create the basis for a new generation of personalized cancer medicine with tailored treatment protocols.

RESEARCH OBJECTIVES AND SCIENTIFIC QUESTIONS

An iron-dependent cell death as a subject of research

THE FOLLOWING VIDEO EXPLORES SCIENTIFIC QUESTIONS:

How can new findings in tumor research be systematically investigated?

And how can interfering factors - such as possible interactions with certain substances in experimental protocols - be identified?

Known substance with extended research approaches?

The video also outlines a well-founded presentation of ferroptosis research, with the focus on reclassifying high-dose vitamin C scientifically:

High-dose vitamin C administration shows varying results in studies

Does ferroptosis research offer new explanations for this variability by investigating specific cellular mechanisms?

The scientifically interesting thing:

The Fenton reaction describes the mechanism - how divalent iron and H₂O₂ generate reactive oxygen species.

And for those interested in science:

The Fenton reaction elegantly explains the mechanism - how divalent iron and H₂O₂ produce the most aggressive radical in the human body.

NOTE: The following video documents a specialist congress lecture. The contents represent the scientific discourse and are not a therapy recommendation. Therapeutic applications require official approval and medical supervision.

A cell death mechanism that was only discovered in 2012 and is the subject of current research.

HIGH-DOSE VITAMIN C IN THE SCIENTIFIC DEBATE

Known substance, new research perspectives: High-dose vitamin C administrations show varying results in studies. Ferroptosis research is investigating possible explanations for this variability by analyzing specific cellular mechanisms.

WHY HEALTHCARE PROFESSIONALS MAY FIND THIS RESEARCH INFORMATION RELEVANT

KEY OBSERVATIONS FROM THE RESEARCH:

Research observations: A scientifically interesting phenomenon

A remarkable phenomenon

In scientific studies, it was observed that cancer cell lines with developed resistance to standard therapies showed different response patterns to ferroptosis-inducing conditions. This observation was made in various resistant cell lines – from vemurafenib-resistant melanoma models to platinum-resistant ovarian carcinoma cell lines and gefitinib-resistant lung carcinoma models.

THE SCIENTIFIC HYPOTHESIS

Research hypotheses assume that resistant cells may adapt their antioxidant defense systems and thus show altered cellular response patterns to oxidative stress.

SYSTEMATIZED SUBSTANCE COORDINATION IN RESEARCH

Experimental protocols in vitamin C research

Various research groups have developed experimental protocols that systematically investigate substance interactions. This involves researching factors that could be relevant in experimental settings:

Perspectives in cancer research

Scientific research is constantly evolving: the combination of Liquid Biopsy with gene expression analysis and individualized research approaches is creating new scientific perspectives for understanding tumor diseases.

The research community is working to deepen our understanding of cancer through innovative diagnostics and individualized research concepts.

Your knowledge advantage starts here:

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Was ist die Testung genetischer Expressionswerte von Krebszellen?

Durch molekularbiologische Analyse identifizieren wir das individuelle Aktionsprofil eines Tumors und finden die therapeutischen Angriffspunkte.

Die Messung der RNA-Genexpressionswerte ist dem Tumorgeschehen näher als eine reine Mutationsanalyse. Mit dieser Messung kann man für wichtige Signalwege des Tumors das konkrete und aktuelle Aktionsprofil und deren Eigenschaften ermitteln.

Per Flüssigbiopsie ist eine Gewinnung frischer lebender Tumorzellen einfach und schmerzfrei möglich.  

Es werden auch Tumorzellen aus Körperregionen gewonnen, die wie in Lunge, Bauchspeicheldrüsen oder Gehirn für herkömmliche Gewebebiopsien oft nur schwierig zu erreichen sind.

Man kann weiterhin auch Tumorzellen aus Urin, Aszites oder Liquor erhalten.

Wenn Gewebebiopsate vorliegen, kann man auch diese nutzen. Somit sind vielfältige Möglichkeiten gegeben, um Tumorzellen zu gewinnen.

Die iSelect und iComplete Tests liefern entscheidende Erkenntnisse bezüglich:

• der Aggressivität des Tumors

• der Manipulation des Immunsystems durch den Tumor

• der Resistenzen gegenüber Medikamenten

• der Aktivität relevanter Signale

• der Wirksamkeit bestimmter Substanzen

Die Messergebnisse werden therapeutischen Substanzen zugeordnet, basierend auf anerkannten Studien, sodass der behandelnde Arzt Optionen für eine gezielte Therapie erhält.

Üblicherweise werden die Tumorzellen aus einer Blutprobe extrahiert, gefolgt von der Analyse der RNA, um die Aktivität von Genen zu bestimmen. Die Tumorzellen können aber auch aus einer Biopsie, Liquor oder Aszites entnommen werden.

Die mit dem iSelect oder iComplete Test gewonnen Therapieoptionen zeigen personalisierte und für den individuellen Tumor zielgerichtete Therapieoptionen auf, die der Therapeut umsetzen kann. Weiterhin werden auch individuell für den vorliegenden Tumor ungeeignete Substanzen die z.B. in der Chemotherapie eingesetzt werden, aufgezeigt. Damit kann man z.B. stark toxische Therapeutika, die der Tumor einfach durchschleust, identifizieren und für die Therapie ausschließen.

Bitte sprechen Sie uns über die kostenlose Beratung an, damit wir den richtigen Test herausfinden und Ihnen die damit verbundenen Kosten mitteilen können.

Die Laborarbeit dauert ca. 10 Arbeitstage. Danach wird ein Bericht geschrieben, der je nach Komplexität des Falles ca. 1 – 3 Arbeitstage dauern kann. Der Bericht muss wegen gesetzlicher Vorgaben im Falle von Krebs an den behandelnden Arzt gehen. Er kann dann den Bericht an den Patienten weiterleiten.

Die Zuverlässigkeit hängt von verschiedenen Faktoren ab, einschließlich der Testmethode und der Qualität der genommenen Probe. In vielen Fällen sind Liquid Biopsy-Tests jedoch eine zuverlässige Ergänzung zu anderen Diagnosemethoden.

1

Contact us and order the blood collection kit for your doctor

Give us a call or send us a message. We will advise you on our tests. We will send the corresponding blood collection kit to your doctor free of charge.

2

Make an appointment for a blood test with your doctor

The blood sample is taken by a doctor you trust or a doctor in our network. Important for chemotherapy patients: Schedule this appointment at the earliest 10-14 days after your last chemotherapy.

3

Take the blood collection kit with you to your doctor's appointment

Bring the blood collection kit you received from us to your doctor’s appointment. After the blood sample has been taken, it will be collected by our courier service and transported to our laboratory.

4

HAVE YOUR DOCTOR COMPLETE THE DOCUMENTS, SIGN THE ORDER and return them to us

  • Check that the enclosed documents are complete
  • Have the doctor complete the order for molecular diagnostics with your consent and signature
  • Complete the enclosed medication plan
  • Enclose copies of your clinic reports/anamnesis
  • Please sign all forms and return the originals to us

5

Your doctor or you:
Inform us about your blood collection appointment

Please let us know when and where the sample is to be collected by e-mail or telephone at least one day before the scheduled blood collection. We need the location, date and a time window of 2 hours for our courier service.

This is the only way we can organize the collection of the sample from your practice.

6

Discuss the results with your doctor

The report is prepared within approx. 10-15 working days after receipt of payment from the patient, depending on the case.

Arrange a consultation with your doctor to discuss the test results. We will send the test report directly to your doctor.

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Contact us at any time

CONTACT FORM DOCTOR

We take the time for you

Contact us at any time

CONTACT FORM PATIENT

We take the time for you

We wish you a pleasant journey